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Pathology of Testicular and Penile Neoplasms - download pdf or read online

By Maurizio Colecchia

ISBN-10: 3319276158

ISBN-13: 9783319276151

ISBN-10: 3319276174

ISBN-13: 9783319276175

This simple publication is a pragmatic advisor to the analysis of testicular tumors and infrequent tumors of the penis. It describes and illustrates pathology findings for every tumor kind and gives details on medical positive aspects, differential prognosis, tumor staging, and prognostic elements. in view that an efficient discussion among urologists and pathologists is vital for optimum sufferer care, due cognizance is paid to such points because the position of frozen part within the administration of small testicular nodules and the exact reporting of testicular and penile neoplasms to make sure that all wisdom required for diagnostic and healing decision-making is obtainable. the major details is gifted in simple tables for ease of reference. This booklet, together with greater than 250 full-color images, is not just a necessary source for surgical pathologists and pathology citizens but in addition a massive reference instrument for all clinicians who deal with sufferers with genitourinary tract tumors.

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Extra resources for Pathology of Testicular and Penile Neoplasms

Example text

1989;129: 800–5. 1 Epidemiology of Testicular Cancer 40. Ford AC, Forman D, Bailey AG, Goodman KJ, Axon AT, Moayyedi P. Effect of sibling number in the household and birth order on prevalence of helicobacter pylori: a cross-sectional study. Int J Epidemiol. 2007;36:1327–33. 41. Trabert B, Zugna D, Richiardi L, McGlynn KA, Akre O. Congenital malformations and testicular germ cell tumors. Int J Cancer. 2013;133:1900–4. 42. Weir HK, Marrett LD, Kreiger N, Darlington GA, Sugar L. Pre-natal and peri-natal exposures and risk of testicular germ-cell cancer.

Deficiency of 17,20 Desmolase The gene that codifies this enzyme has been mapped on chromosome 10. Variable degrees of 17,20 desmolase deficit have been observed, explaining the variability of external genitalia ranging from a female phenotype to minimally virilized males with micropenis, bifid scrotum, perineal hypospadias, and cryptorchidism. This is a result of insufficient testosterone production during fetal life [54]. Histological studies of these testes in infants show decreased numbers of spermatogonia [55, 56].

Some streak gonads with epithelial cord-like structures are devoid of germ cells, although it is probable that this gonad contained germ cells in some moment of its development but were eliminated by an apoptosis mechanism. This is the characteristic gonad of 46,XY gonadal dysgenesis [13–17]. 26 M. Nistal and P. González-Peramato Fig. 6 Streak gonad with epithelial cord-like structures. Streak gonad with nests and cords of cells embedded in a stroma similar to ovarian cortex Fig. 7 Streak gonad with epithelial cord-like structures.

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Pathology of Testicular and Penile Neoplasms by Maurizio Colecchia


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